The objective wase to evaluate Health Knowledge and Practices Among Street Food Vendors In Khartoum State- Sudan. The descriptive cross-sectional study that was carried out, from May 1st,2021 to May 1st, 2022, to assess the knowledge and practices related to food safety among those who sell it on the streets in the 3 cities of Khartoum State, By means of a pretested questionnaire. In addition to making observations about certain topics that were not addressed during the in-depth interviews. 1581workers from a variety of locations participated in the questionnaire, including Nile Street, street sellers, marketplaces, and areas close to hospitals, schools, bus stations, entertainment venues, and other locations. Of them, (44.4%) were men and 55.6% were women. They operate in the food and beverage preparation. The majority of whom are between the ages of 28 - 37, 37.7% know just a little bit about food safety protocols.