Background: Women fertility inhibition research designed to downsize the family in most countries of the world appears to be slow or ineffective in a significant decrease in population growth. Therefore, research attention continues to rise in search of a lasting solution to this dilemma. Objectives: This study was designed to analyze the family size and its socio-economic implications in the Kirehe district of Rwanda with focus on female employment, spousal income, and education. Material and Methods: The study adopted a cross sectional and descriptive design with a quantitative bias, 398 respondents were selected using a purposive and simple random sampling from a population size of 57600 families living in the Kirehe district of Rwanda. The data collection instruments were; questionnaire and documentary Analysis while primary and secondary sources of data were used. Data analysis for descriptive statistical relevance with appropriate tools were done using SPSS. Results and conclusion: From the result of this study, there was no association between family size and health of the family, educational background of respondents, education attainment of children, spousal income, and female employment. Recommendations: Behavior modification and attitude change towards gender preference, increase in women literacy for women empowerment, personalized counseling, guidance and follow up regarding birth control measures, are highly recommended.