Non-invasive continuous glucose monitoring has emerged as animportant solution for managing diabetes and maintaining metabolic health. Wearable biosensor technologies have contributed this field by offering real-time monitoring of glucose levelin minimally-invasive way, enabling improved patient compliance and enhanced disease management. This article reviews the latest advancements in wearable biosensor systems, especially focusing on sweat-based glucose monitoring method. We highlight clinical requirement in patient-care, essential approaches to develop the wearable biosensor seamlessly integrated with skin and principles of glucose monitoring from sweat. It highlights innovations in materials, device integration, considering sensor performance in terms of accuracy, stability, and biocompatibility. Finally, we explore future directions for wearable glucose sensors, emphasizing the potential for multi-analyte detection and personalized health management systems. By bridging cutting-edge research with clinical applications, this work underscores the transformative potential of wearable biosensors in revolutionizing diabetes care and beyond.