The establishment of the Western school is initiated in most African countries by missionaries. In Cameroon, Protestants are the pioneers in this area. They have created many school structures. The effectiveness of these schools can be measured by several factors including the qualification of teachers. These constitute an essential link in academic success. This study therefore focuses on a critical analysis of the role played by teaching staff in the implementation of the western school in Cameroon. It is based on a method that is both qualitative and quantitative. By relying on the missions assigned to teachers in Protestant schools, it emerges that they have been a vector of the acculturation or even the westernization of the Cameroonian population. In turn, they participated in the alienation of students from the traditional school or their culture. The sources used are both written and oral, official and unofficial.