Lisch nodules, one of the hallmark manifestations of neurofibromatosis type 1

Von Recklinghausen disease or neurofibromatosis type I (NF1) is the most common phacomatosis. Inherited forms are transmitted in an autosomal dominant fashion. Lisch nodules are the most common ophthalmological manifestation of NF1, reported in 73-95% of cases. We report the case of a 49-year-old female patient, referred to ophthalmology for a systematic ocular check-up in view of the following cutaneous signs: café-au-lait spots and multiple neurofibromas.