Primary cutaneous follicle center lymphoma treated with rituximab: A case report

Rationale: Cutaneous B-cell lymphomas comprises a group of lymphoproliferative neoplasms of the B-cell non-Hodgkin's lymphoma type with extra nodal location, this type of neoplasms are indolent, so mainly it affects the cutaneous tissue, without any other type of systemic clinical manifestation. Patient concerns: A 53-year-old male with no chronic degenerative history, who came for evaluation due to the appearance of dermal lesions at the thorax. Diagnoses: Within the classification of cutaneous lymphomas, primary cutaneous follicle center lymphoma is mainly characterized by the appearance of dermal lesions of papules and erythematous plaques which expresses a phenotype with CD20+, CD79a+, CD5-, CD10+/-, BCL 6+ and MUM-1/IRF-4 negative. Outcomes. The use of biological agents (rituximab) combined with a surgical excision as the treatment for this neoplasm have a complete response in this type of primary lymphoma.