The Primary Sector, the support of the world economy, is undergoing serious transformations, such as the breaking of links in productive chains, incorporating transnational actors into the production of natural products and boosting the industrial, commercial and services sector; which has been subject to strengthening, in important countries of the world as well as in emerging economies. For this reason, the case of tomato in Mexico is addressed, in producing areas, to determine the degree of participation of actors of the productive group in the value chain, suggest alternatives and solution improvements in production, and the participation of groups of interest; the cultivation, harvesting and marketing of tomatoes; exposition of the productive chain and integration based on the quintuple helix model, (Carayanis and Campbell, 2012), the objective of this article is to analyze the productive articulation in tomato production in Mexico and the participation of the various actors, companies, government, academia and society to know the scope and challenges for the future. The methodology is a qualitative approach based on content analysis, identification of areas of opportunity to counteract dysfunctions and government support for the sector.