The study of health and disease in a specific population, including its causes, manifestations, and distribution, is known as epidemiology. The reproduction of organisms in host tissue is called infection, which can lead to illness. A carrier is a person who carries infectious germs but does not exhibit any apparent symptoms. The spread of the organism in its surroundings is known as dissemination. The etiologic agent, the mode of transmission (by contact, by a shared vehicle, by air or a vector), and the host are the three main factors that contribute to disease occurrence.Epidemiologic studies may be (1) descriptive, organizing data by time, place, and person; (2) analytic, incorporating a case-control or cohort study; or (3) experimental. This method can potentiallystudy the diseases, their distribution, severity, prevalence and incidence ratio at a particular place in a specific time.