TREND ANALYSIS AND DETERMINANTS OF MATERNAL OUTCOMES OF SEVER PREECLAMPSIA AND ECLAMPSIA AT DEBRE MARKOS REFERRAL HOSPITAL, NORTHWEST ETHIOPIA 2018: RETROSPECTIVE STUDY DESIGN

Introduction: Preeclampsia/eclampsia has remained a significant public health threat in both developed and developing countries contributing to maternal morbidity and mortality globally. Aim: This study aimed to assess trend analysis and determinants of maternal outcomes of preeclampsia and Eclampsia. Methods: Institutional based retrospective cross-sectional study on 289 women who diagnosed as preeclampsia/eclampsia in Debre Markos Referral Hospital. Results: Trends of the occurrences of preeclampsia/eclampsia increased from 2013 to 2017 by 12.75 times. Of the 289 mothers with preeclampsia/eclampsia, 63.3% had experienced at least one maternal complication over the five-year period. The number of women with at least one type of maternal complication increased from 2013 to 2017 by 20.67 times. The main complications were HELLP syndrome (45.4%) and maternal death (25.2%). Mothers who took Hydralazine and diazepam were less likely to develop complications than who didn’t take the drug. Conclusion: An increasing trend of preeclampsia/eclampsia and maternal complications were observed over a five years’ period in the study area. Therefore, efforts would be strengthening to end the increased trend of preeclampsia/eclampsia and maternal complications both in the community and the health institutions. Introduction: Preeclampsia/eclampsia has remained a significant public health threat in both developed and developing countries contributing to maternal morbidity and mortality globally. Aim: This study aimed to assess trend analysis and determinants of maternal outcomes of preeclampsia and Eclampsia. Methods: Institutional based retrospective cross-sectional study on 289 women who diagnosed as preeclampsia/eclampsia in Debre Markos Referral Hospital. Results: Trends of the occurrences of preeclampsia/eclampsia increased from 2013 to 2017 by 12.75 times. Of the 289 mothers with preeclampsia/eclampsia, 63.3% had experienced at least one maternal complication over the five-year period. The number of women with at least one type of maternal complication increased from 2013 to 2017 by 20.67 times. The main complications were HELLP syndrome (45.4%) and maternal death (25.2%). Mothers who took Hydralazine and diazepam were less likely to develop complications than who didn’t take the drug. Conclusion: An increasing trend of preeclampsia/eclampsia and maternal complications were observed over a five years’ period in the study area. Therefore, efforts would be strengthening to end the increased trend of preeclampsia/eclampsia and maternal complications both in the community and the health institutions.