This study is for the purpose of examining the effect of entrepreneurship skills embraced by the youths on unemployment in Ijebu-East Local Government (IELG). Ijebu-Imushin and Ogbere were selected randomly out of the five major towns in IELG namely Itele Ijebu, Ijebu Ife, Imobi, Ijebu Imushin and Ogbere from where 100 respondents whose ages ranges between 20 and 35 years were selected using the method of random sampling. Data were collected from the respondents using structured questionnaires due to the similarities in their socio-cultural characteristics. The collected data were analyzed using descriptive and inferential statistics. The T-test result shows that entrepreneurship can be used to solve the challenge of unemployment in the study area since the hindering factors are not significant as shown the result of the chi square, which implies that, it can be used for the transformation of Nigeria into a technologically and economically developed country because of its abundant active youths that are full of vibrant innovative ideas. The author therefore recommended that, Government should design policies that are purposively for the developing and promotion of entrepreneurship skills.