Invitro composition and the effects of ethanol extract of Gongronema Latifolium (Benth) fruit on some biochemical parameters in albino rats

The purpose of the study was to evaluate the invitro composition and the effects of ethanol extract of G. latifolium fruit on some biochemical parameters in albino rats. Acute toxicity study was carried out with eighteen (18) albino rats using lorke’s method. Thirty-five (35) albino rats weighing between 90-105grams were acclimatized for 7days, divided into 5 groups of 7 rats per group. Group A is the normal control while Groups B, C, D, and E received 100, 200, 300 and 500mg/kg bodyweight extract respectively. The in vitro and in vivo antioxidant activities, reducing power and inhibition of lipid peroxidation were determined spectrophotometrically.